LOCUS       AY128640                 510 bp    DNA     linear   VRL 12-DEC-2003
DEFINITION  Human adenovirus type 35 strain Holden, complete genome.
ACCESSION   AY128640 REGION: 33100..33609
VERSION     AY128640.2  GI:38196041
KEYWORDS    .
SOURCE      Human adenovirus 35
  ORGANISM  Human adenovirus 35
            Viruses; dsDNA viruses, no RNA stage; Adenoviridae; Mastadenovirus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Gao,W., Robbins,P.D. and Gambotto,A.
  TITLE     Human adenovirus type 35: nucleotide sequence and vector
            development
  JOURNAL   Gene Ther. 10 (23), 1941-1949 (2003)
   PUBMED   14528318
REFERENCE   2  (bases 1 to 510)
  AUTHORS   Gao,W., Robbins,P.D. and Gambotto,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2002) Surgery, University of Pittsburgh, 300
            Technology Drive, Pittsburgh, PA 15219, USA
REFERENCE   3  (bases 1 to 510)
  AUTHORS   Gao,W., Robbins,P.D. and Gambotto,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2003) Surgery, University of Pittsburgh, 300
            Technology Drive, Pittsburgh, PA 15219, USA
  REMARK    Sequence update by submitter
COMMENT     On Nov 6, 2003 this sequence version replaced gi:35670771.
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Human adenovirus 35"
                     /mol_type="genomic DNA"
                     /strain="ATCC VR-718; Holden"
                     /db_xref="ATCC:VR-718"
                     /db_xref="taxon:10522"
     CDS             complement(<1..146)
                     /codon_start=1
                     /product="E4 122R protein"
                     /protein_id="AAN17497.1"
                     /db_xref="GI:35670800"
                     /translation="MVLPSLPSPLLLETQSSCIAWLGFAYATVDDFLRTIRCDGVLIT
                     TEASILLTNLRVWLYLNYHTEHAKRQDRRRRRVCSARAAFCYTKYENVRKQLHYDKVA
                     RTLDIMRQTSPLHQSPVTTL"
     misc_RNA        1..510
                     /note="VA RNA region"
     CDS             complement(155..508)
                     /codon_start=1
                     /product="E4 117R protein"
                     /protein_id="AAN17496.1"
                     /db_xref="GI:35670799"
                     /translation="MRVCLRMVVEGALRDLFVMCGLDLPQELTRIIQGWKAENYLGMV
                     QECNMMIEELENAPSFGILLFLDVRVEALLEATVEHLENRISFDLAVLFHQHSGGERC
                     HLRDLQFEVLRDRLE"
     CDS             complement(505..>510)
                     /codon_start=1
                     /product="E4 145R protein"
                     /protein_id="AAN17499.1"
                     /db_xref="GI:35670802"
                     /translation="MTLVFFLFLQTNSKLTMLERSAVTYCICIPEVLNVFLANFSFIQ
                     FLQETLPDYISSNFDDITGGSQYAYSNLVFAGANWGGLRLYCTVASPALVPGGLLAKQ
                     FGDNMREFLQLELKEELRAKGMSIDVAILNSLQVTQEQDILSL"
ORIGIN      
        1 atgctggctt cagttgtaat caaaactcca tcgcatctaa ttgttctgag gaaatcatcc
       61 acggtagcat atgcaaatcc caaccaagca atgcaactgg attgcgtttc aagcaggaga
      121 ggagagggaa gagacggaag aaccatgtta atttttattc caaacgatct cgcagtactt
      181 caaattgtag atcgcgcaga tggcatctct cgcccccact gtgttggtga aaaagcacag
      241 ctaaatcaaa agaaatgcga ttttcaaggt gctcaacggt ggcttccaac aaagcctcca
      301 cgcgcacatc caagaacaaa agaataccaa aagaaggagc attttctaac tcctcaatca
      361 tcatattaca ttcctgcacc attcccagat aattttcagc tttccagcct tgaattattc
      421 gtgtcagttc ttgtggtaaa tccaatccac acattacaaa caggtcccgg agggcgccct
      481 ccaccaccat tcttaaacac accctcataa
//