LOCUS DQ393829 3276 bp DNA linear VRL 12-SEP-2006
DEFINITION Human adenovirus type 49, complete genome.
ACCESSION DQ393829 REGION: 4997..8272
VERSION DQ393829.1 GI:88810171
KEYWORDS .
SOURCE Human adenovirus 49
 ORGANISM Human adenovirus 49
  Viruses; dsDNA viruses, no RNA stage; Adenoviridae; Mastadenovirus;
 Human adenovirus D.
REFERENCE 1 (bases 1 to 3276)
 AUTHORS Lemckert,A.A.C., Grimbergen,J., Smits,S., Hartkoorn,E.,
 Holterman,L., Berkhout,B., Barouch,D.H., Vogels,R., Quax,P.,
 Goudsmit,J. and Havenga,M.J.E.
 TITLE Generation of a novel replication-incompetent adenoviral vector
 derived from human adenovirus type 49: manufacture on PER.C6 cells,
 tropism and immunogenicity
 JOURNAL J. Gen. Virol. 87 (PT 10), 2891-2899 (2006)
 PUBMED 16963747
REFERENCE 2 (bases 1 to 3276)
 AUTHORS Lemckert,A.A.C., Grimbergen,J., Smits,S., Hartkoorn,E.,
 Berkhout,B., Barouch,D.H., Vogels,R., Quax,P., Goudsmit,J. and
 Havenga,M.J.E.
 TITLE Direct Submission
 JOURNAL Submitted (08-FEB-2006) Crucell Holland BV, P.O. Box 2048, Leiden
 2301 CA, The Netherlands
FEATURES Location/Qualifiers
 source 1..3276
 /organism="Human adenovirus 49"
 /mol_type="genomic DNA"
 /db_xref="taxon:218120"
 CDS complement(<1..340)
 /codon_start=1
 /product="pIVa2"
 /protein_id="ABD52386.1"
 /db_xref="GI:88810173"
 /translation="MSRLRALFQGQAPRQGPRRRGPQLRAHGQLLSRRRAGRRPCPFQ
 HQQDESQAHPCKRPARGPPIHRDGDHPHSDPETLEGHDAGRAGRPSSRALQSQSSQPP
 KRGSLLDRDAVEHVTELWDRLELLSQTLAKMPMADGLKPLKNFASLQELLSLGGDRLL
 GELVRENLQVRDMLNEVAPLLRDDGSCMSLNYHLQPVIGVIYGPTGCGKSQLLRNLLS
 SQLITPAPETVFFIAPQVDMIPPSEMKAWEMQICEGNFAPGPEGTIVPQSGTLRPKFI
 KMSYDDLTQEHNYDVSDPRNVFAKAAAHGPIAIIMDECMENLGGHKGVSKFFHAFPSK
 LHDKFPKCTGYTVLVVLHNMNPRRDLGGNIANLKIQAKLHIISPRMHPSQLNRFANTY
 TKGLPVAISLLLKDIIQHHAQRPCYDWIIYNTTPEHEAMQWCYLHPRDGLMPMYLNIQ
 SHLYRVLEKIHRTLNDRERWTRAYRARKNK"
 CDS complement(1..3276)
 /codon_start=1
 /product="DNA polymerase"
  /protein_id="ABD52387.1"
 /db_xref="GI:88810174"
 /translation="MQCVDTATNSPVEIKYHLHLKHALTRLYEVNLRTLPPDLDLRDT
 MDSSQLRALVFALRPRRAEIWTWLPRGLVSLSVLEEPQGESHAGEHENHQPGPPLLKF
 LLKGRAVYLVDEVQPVQRCEYCGRFYKHQHECSVRRRDFYFHHINSHSSNWWQEIQFF
 PIGSHPRTERLFVTYDVETYTWMGSFGKQLVPFMLVMKFSGDPKLVALARDLAVRLRW
 DRWERDPLTFYCVTPEKMAVGQQFRLFRDELQTLMARELWASFMQANPHLQEWALEQH
 GLQCPEDLTYEELKKLPHIKGRPRFMELYIVGHNINGFDEIVLAAQVINNRASVPGPF
 RITRNFMPRAGKILFNDVTFALPNPLSKKRTDFELWEHGGCDDSDFKYQFLKVMVRDT
 FALTHTSLRKAAQAYALPVEKGCCPYKAVNHFYMLGSYRADDRGFPLREYWKDDEEYA
 LNRELWEKKGEAGYDIIRETLDYCAMDVLVTAELVAKLQDSYAHFIRDSVRLPHAHFN
 IFQRPTISSNSHAIFRQIVFRAEQPQRTNLGPAFLAPSHELYDYVRASIRGGRCYPTY
 IGILSEPIYVYDICGMYASALTHPMPWGPPLNPYERALAAREWQMALDDASSKIDYFD
 KELCPGIFTIDADPPDEHLLDVLPPFCSRKGGRLCWTNEPLRGEVATSVDLVTLHNRG
 WRVRIVPDERTTVFPEWKCVAREYVQLNIAAKERADRDKNQTMRSIAKLLSNALYGSF
 ATKLDNKKIVFSDQMDESLLKSIAAGQANIKSSSFLETDNLSAEVMPALEREYLPQQL
  ALVDSDAEESEDEHRPAPFYTPPSGTPGHVAYTYKPITFLDAEEGDMCLHTVEKVDPL
 VDNDRYPSHVASFVLAWTRAFVSEWSEFLYEEDRGTPVQDRPIKSVYGDTDSLFVTER
 GHRLMETRGKKRIKKNGGKLVFDPEQPELTWLVECETVCAHCGADAFAPESVFLAPKL
 YALQSLLCPACGRSSKGKLRAKGHAAEALNYELMVNCYLADAQGEDRARFSTSRMSLK
 RTLASAQPGAHPFTVTETTLTRTLRPWKDMTLAALDAHRLVPYSRSRPNPRNEEVCWI
 EMP"
ORIGIN 
 1 ctacggcatc tcgatccagc agacttcctc gtttcggggg ttgggacgac tgcgactgta
 61 gggcacgaga cgatgggcgt ccagcgcggc cagcgtcatg tccttccagg gtctcagggt
 121 ccgagtgagg gtggtctccg tcacggtgaa tgggtgggcc ccgggctggg cgcttgcaag
 181 ggtgcgcttg agactcatcc tgctggtgct gaaacgggca cggtcttcgc cctgcgcgtc
 241 ggcgagatag cagttgacca tgagctcgta gttgagggcc tcggcggcgt ggcccttggc
 301 gcggagcttg cccttggaag agcgcccgca ggcgggacat aggagggatt gcagggcgta
 361 tagcttgggt gcgagaaaga cggactcggg agcgaaggcg tctgctccgc agtgggcgca
 421 gacggtctcg cactcgacga gccaggtgag ctcgggctgc tcggggtcaa aaaccagttt
 481 tcccccgttc tttttgatgc gcttcttacc tcgcgtctcc atgagtctgt gtccgcgctc
 541 ggtgacaaac aagctgtctg tgtccccgta gacggacttg atgggcctgt cctgcacggg
 601 cgtcccgcgg tcctcctcgt agagaaactc ggaccactct gagacgaagg cgcgcgtcca
 661 cgccaagaca aaggaggcca cgtgcgaggg gtagcggtcg ttgtccacca gggggtccac
 721 cttttccacc gtgtgcagac acatgtcccc ctcctccgca tccaagaagg tgattggctt
 781 gtaggtgtag gccacgtgac cgggggtccc cgacgggggg gtataaaagg gggcgggtct
 841 gtgctcgtcc tcactctctt ccgcgtcgct gtccacgagc gccagctgtt ggggtaggta
 901 ttccctctcg agagcgggca tgacctcagc actcaggttg tcagtttcta gaaacgagga
 961 ggatttgatg ttggcctgcc ctgccgcgat gctttttagg agactttcat ccatctggtc
 1021 agaaaagact atttttttat tgtcaagctt ggtggcgaag gagccatata gggcgttgga
 1081 gagaagcttg gcgatggatc tcatggtctg atttttgtca cggtcggcgc gctccttggc
 1141 cgcgatgttg agctggacat actcgcgcgc gacgcacttc cattcgggga agacggtggt
 1201 ccgctcgtcg ggcacgatcc tgacgcgcca gccgcggtta tgcagggtga ccaggtccac
 1261 gctggtggcc acctcgccgc gcaggggctc gttggtccag cagagtctgc cgcccttgcg
 1321 cgagcagaac ggaggcagca catcaagcag atgctcgtca ggggggtccg catcgatggt
 1381 gaagatgccc ggacagagtt ccttgtcaaa ataatctatt tttgaggatg catcatccaa
 1441 ggccatctgc cactcgcggg cggccagcgc tcgctcgtag gggttgaggg gcgggcccca
 1501 gggcatggga tgcgtgaggg cggaggcgta catgccgcag atgtcgtaga catagatggg
 1561 ctccgagagg atgccgatgt aggttggata acagcgcccc ccgcggatgc tggcgcgcac
 1621 gtagtcatac aactcgtgcg agggggccaa gaaggcgggg ccgagattgg tgcgctgggg
  1681 ctgctcggcg cggaagacga tctggcgaaa gatggcgtgc gagttggagg agatggtggg
 1741 ccgttggaag atgttaaagt gggcgtgggg caggcggacc gagtcgcgga tgaagtgcgc
 1801 gtaggagtct tgcagcttgg cgacgagctc ggcggtgacg aggacgtcca tggcgcagta
 1861 gtccagcgtt tcgcggatga tgtcataacc cgcctctcct ttcttctccc acagctcgcg
 1921 gttgagggcg tactcctcgt catccttcca gtactcccgg agcgggaatc ctcgatcgtc
 1981 cgcacggtaa gagcccagca tgtagaaatg gttcacggcc ttgtagggac agcagccctt
 2041 ctccacgggg agggcgtaag cttgagcggc cttgcggagc gaggtgtgcg tcagggcgaa
 2101 ggtgtccctg accatgactt tcaagaactg gtacttgaag tccgagtcgt cgcagccgcc
 2161 gtgctcccag agctcaaaat cggtgcgctt cttcgagagg gggttaggca gagcgaaagt
 2221 gacgtcattg aagagaatct tgcctgcccg cggcatgaaa ttgcgggtga tgcggaaagg
 2281 accagggacg gaggctcggt tgttgatgac ctgggcggcg aggacgatct cgtcgaagcc
 2341 gttgatgttg tgcccgacga tgtagagttc catgaatcgc gggcggcctt tgatgtgcgg
 2401 cagctttttg agctcctcgt aggtgaggtc ctcggggcat tgcaggccgt gctgctcgag
 2461 cgcccactcc tggagatgtg ggttggcttg catgaaggaa gcccagagct cgcgggccat
 2521 gagggtctgg agctcgtcgc gaaagaggcg gaactgctgg cccacggcca tcttttctgg
 2581 ggtgacgcag tagaaggtga gggggtcccg ctcccagcga tcccagcgta agcgcacggc
 2641 gagatcgcga gcgagggcga ccagcttggg gtcccccgag aatttcatga ccagcatgaa
 2701 ggggacgagc tgcttgccga aggaccccat ccaggtgtag gtttctacat cgtaggtgac
 2761 aaagagccgc tccgtgcgag gatgagagcc gattgggaag aactggattt cctgccacca
 2821 gttggacgag tggctgttga tgtgatgaaa gtagaaatcc cgccggcgaa ccgagcactc
 2881 gtgctgatgc ttgtaaaagc gtccgcagta ctcgcagcgc tgcacgggct gtacctcatc
 2941 cacgagatac acagcgcgtc ccttgaggag gaacttcagg agtggcggcc ctggctggtg
 3001 gttttcatgt tcgcctgcgt gggactcacc ctggggctcc tcgaggacgg agaggctgac
 3061 gagcccgcgc gggagccagg tccagatctc ggcgcggcgg gggcggagag cgaagacgag
 3121 ggcgcgcagt tgggagctgt ccatggtgtc gcggagatcc aggtccgggg gcagggttct
 3181 gaggttgacc tcgtagaggc gggtgagggc gtgcttgaga tgcagatggt acttgatttc
 3241 tacgggtgag ttggtggccg tgtccacgca ttgcat
//