----------------------------------------------------------------------- BIOINFORMATICS COLLOQUIUM School of Computational Sciences George Mason University ----------------------------------------------------------------------- Theoretical Studies of Light Harvesting Proteins Ana Damjanovic, Ph.D. Johns Hopkins University Tuesday, March 16, 2004 4:30 pm PW2 Auditorium, Prince William Campus Photosynthetic organisms utilize sunlight to drive their cellular reactions. Through natural selection, the light harvesting apparatii of various life forms were optimized for high efficiency in particular habitats. For several organisms, x-ray crystallography has revealed the arrangement of photo-active molecules, chlorophylls and carotenoids in light-harvesting proteins. Through structure based molecular dynamics and quantum calculations we reveal the design principles underlying efficient absorption and energy transfer, and how these molecules cope with physiological temperatures, where thermal disorder is significant. Thus, the natural photo cell, as engineered and optimized by evolution, provides clues invaluable for design of efficient artificial nano-scale light harvesting antennae and photo cells. ---------------------------------------------------------------------- Refreshments are served at 4:00 pm. Find the schedule and directions at http://www.binf.gmu.edu/colloq.html