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                       BIOINFORMATICS COLLOQUIUM
                    School of Computational Sciences
                        George Mason University
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And We mean High-Throughput:Upcoming Issues in Cancer Genomics Research

                       Meredith Yeager-Jeffery, Ph.D.
                Scientific Director, Core Genotyping Facility
                       Advanced Technology Center
                       National Cancer Institute


                       Tuesday, January 31, 2006
                               4:30 pm
               Verizon Auditorium, Prince William Campus




Recent advances in human genomics, including the availability of new 
extremely high-throughput technologies, have significantly changed the 
landscape of cancer research.  One place where these technologies are 
extremely attractive is in epidemiological studies that seek contrasts 
in the genetics of those afflicted with a specific type of cancer 
versus that of the general population.  Many of these studies utilize a 
common form of variation among humans, the single nucleotide 
polymorphism (SNP).  Analyses of genetic markers have been going on for 
decades, though on a scale orders of magnitude smaller than what is 
possible today.  In the early days, “high throughput” meant generating 
tens of genotypes per day; it is now possible to generate tens of 
millions.  Generating this much data poses many interesting 
bioinformatic and analytic challenges.

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Refreshments are served at 4:00 pm. Find the schedule and directions at
http://www.binf.gmu.edu/colloq.html