ADENOVIRUS GENOME DIVERSITY

Alignment of the Complete Genomic Sequences of Human Adenoviruses 02, 05, 12, 17, and 40

by Raja Mazumder and Don Seto

Methodology

Ad2 and Ad5 were aligned with MAP [Xiaoqiu 1994]. Results were modified and saved in UNIX Text Editor JOT.

Consensus sequence of Ad2 and Ad5 was generated in GCG.

Ad17 was then aligned to the consensus of Ad2 and Ad5, and another consensus was created from the alignment.

This step was repeated with Ad40 and Ad12 so that all the genomes could be aligned.

All the alignments were imported into GCG for viewing and/or further editing.

The gaps present at the end of the alignments were deleted.

Results

Please click here to view the entire 71 page alignment result

Please click here to view a condensed 1 page alignment result

Please click here to view the stringent alignment result of Ad01_b with Ad02

Please click here to view the less stringent alignment result of Ad01_b with Ad02

Reference

1. Huang Xiaoqiu. 1994. On global sequence alignment. Computer Applications in the Biosciences. 10:227-235

Adenovirus sequences

HAd2 (FASTA format) (GenBank link)
HAd5 (FASTA format) (GenBank link)
HAd12 (FASTA format) (GenBank link)
HAd17(FASTA format) (GenBank link)
HAd40(FASTA format) (GenBank link)
MAd1 (GenBank link)

Novel Adenovirus sequences being sequenced, assembled and analyzed in the laboratory

Ad1
Ad2
Ad5
Ad6
Ad7

Contributors

Vladimir Krasnov, Jason Seto, Julie Street, and Clark Tibbetts. IB3/GMU.
Ashok Kolaskar, Charles Buck. ATCC.
Stephen McCormack. Keck Graduate School.
Raja Mazumder, Eric Blair, and Donald Seto. IB3/GMU

Note

Adenovirus reference list

If you have any questions please e-mail Raja Mazumder or Don Seto