BINF 732 – Genomics

Course Time: Wednesday 4:30-7:10 pm
Course Location : Occoquan Building, Room 327, Prince William Campus
Instructor : Saleet Jafri, 703-993-8420, sjafri@gmu.edu
Office Hours : By appointment in Krasnow Institute Room 234
Course Web Page : http://www.binf.gmu.edu/jafri/binf732/
Prerequisites: Computer knowledge and previous courses in biology, or permission of instructor
Textbook: Discovering Genomics, Proteomics, and Bioinformatics by Campbell and Heyer 2nd Edition

Course Description:
Surveys computational tools and techniques to study whole genomes and explores biological basis of genome analysis algorithms. Topics include genome maping, comparative genomics, and functional genomics.

Grading Policy:
The course grade will be determined as follows:
                                                        90-100     A
Mid-Term Exam - 30%                80-89.9    B
Final Exam - 40%                          80-89.9    C
Final Project - 30%                       70-79.9    F

Problem sets will be assigned as homework several times during the semester. They will be due two weeks after they are assigned. The assignments will be posted on the course web page.  Late homeworks will not be accepted.

Academic Honesty Policy:
Academic dishonesty will not be tolerated. This includes cheating, plagiarism, and falsification of academic records. That being said, you can help each other out on the homework (this does not mean that you can copy each other's homework).

Important Dates (Under revision):
Wednesday, August 28 - First Day of Class
Wednesday, October 23 - Take-home Mid-Term Exam Posted
Wednesday, October 30 - Take-home Mid-Term Exam Due
Wednesday, November 27 - No class due to Thankgiving Holiday
Wednesday, December 4 - Project Presentations - Last Day of Class
Wednesday, December 11 - Final Exam 4:30-7:15

Course Schedule

Wednesday, August 28, 2013 - Introduction to Genomics (Jafri) - Chapter 1
Wednesday, September 4, 2013 - Cell Signaling and Genomics (Jafri) - Chapter 10-12
Wednesday, September 11, 2013 - Cell Signaling and Genomics (Jafri) - Chapter 10-12
Wednesday, September 18, 2013- Molecular Modeling and Genomics (Klimov) - Chapter 8
Wednesday, September 25, 2013- Structural Genomics (Vaisman) - Chapter 8
Wednesday, October 2, 2013- Sequencing and Annotation (Seto) - Chapter 2
Wednesday, October 9, 2013- Viral Genomics (Seto) -
Wednesday, October 16, 2013- Functional Genomics (Baranova)- Chapters 6-7
Wednesday, October 23, 2013- Agricultural Genomics (Jafri) - Readings in Notes
Wednesday, October 30, 2013- Agricultural Genomics (Munkvold) - Take-home Midterm Due
Wednesday, November 6, 2013- Genome Expression (Higgs) and TBA - Chapter 6-7
Wednesday, November 13, 2013- Human Genomics Variation and Pharamacogenomics (Jafri)- Chapters 4,5,and 9
Wednesday, November 20, 2013- Forensics and Mitochondrial Genomics (Wilson) - Chapters 3-4
Wednesday, November 27, 2013- No class - Thankgiving
Wednesday, December 4, 2013- Final Project Presentations
Wednesday, December 11, 2013- Final Exam

Sage Advice: If you want to do well in course: 1) Do all the problem sets. 2) Read the text book and any other assigned reading. 3) Ask questions in class and office hours. 3) If you are having difficulty doing the problem sets, be sure to get help.  I encourage the students discussing the course material and problems, but require everyone to do the work - NO COPYING.



Saleet Jafri
Tuesday August 27, 2013