Course Description:
Surveys computational tools and techniques to study whole genomes and explores biological basis of genome analysis algorithms. Topics include genome maping, comparative genomics, and functional genomics.
Grading Policy:
The course grade will be determined as follows:
90-100 A
Mid-Term Exam - 30%
80-89.9 B
Final Exam - 40%
70-79.9 C
Final Project -
30%
70-79.9 F
Problem sets will be assigned as homework several times during the semester. They will be due two weeks after they are assigned. The assignments will be posted on the course web page. Late homeworks will not be accepted.
Academic Honesty Policy:
Academic dishonesty will not be tolerated. This includes cheating, plagiarism, and falsification of academic records. That being said, you can help each other out on the homework (this does not mean that you can copy each other's homework).
Important Dates :
Monday, January 26 - First Day of Class
Monday, March 9 - No Class - Spring Break
Monday, March 16 - Take-home Mid-Term Exam Posted
Monday, March 23 - Take-home Mid-Term Exam Due
Monday, April 27 and May 5 - Project Reports Due and Project Presentations
Monday, May 4 - Project Presentations and Final Exam Posted - Last Day of Class
Course Schedule
Lecture 1 - Introduction to Genomics -January 26, 2026
Lectuer 2 - Multiscale view of Genomics:Cardiac Calcium Signaling - February 2, 2026
Lectuer 3 - Multiscale view of Genomics:Transcription Factors - February 9, 2026
Lecture 4 - Sequencing and Annotation - February 16, 2026
Lecture 5 - Genomes of Populations - March 2, 2026
Lecture 6 - Genomic Variation - March 16, 2026
Lecture 7 - Clinical Genomics - March 23, 2026
Midterm Exam Due - March 23, 2026
Lecture 8 - Functional Genomics - March 30, 2026
Lecture 9 - Epigenomics - April 6, 2026
Lecture 10 - Agricultural Genomics - April 13, 2026
Lecture 11 - Mitochondrial Genomics - April 20, 2026
Lecture 12 - Pharmacogenomics - April 27, 2026
Final Projects Reports Due - April 27, 2026
Final Project Presentations - April 27, 2026
Final Project Presentations - May 4, 2026
Final Exam Posted - May 4, 2026
Final Exam Due - May 11, 2026
Sage Advice: If you want to do well in course: 1) Do all the problem sets. 2) Read the text book and any other assigned reading. 3) Ask questions in class and office hours. 3) If you are having difficulty doing the problem sets, be sure to get help. I encourage the students discussing the course material and problems, but require everyone to do the work - NO COPYING.